The safety of azelaic acid during pregnancy
Azelaic acid has been widely used in the field of skin care. However, the safety of this substance in pregnant women is a matter of great concern.

The current studies show that the structure of azelaic acid is relatively simple, and its metabolism in the body is clear. In animal experiments, high doses of azelaic acid administered to pregnant animals have not been found to have significant adverse effects such as teratogenicity and embryonic toxicity. Its mechanisms of action mostly involve inhibition of microbial protein synthesis, anti-inflammatory, etc. However, these mechanisms have not caused significant negative linkage in the physiological environment during pregnancy.

Clinically, although large-scale data on the use of azelaic acid in pregnant women are insufficient, limited case reports and small sample studies show that local use of azelaic acid in pregnant women has not seen serious maternal and infant adverse outcomes related to drug use. Some pregnant women use azelaic acid-containing preparations as directed by doctors due to common acne, and the pregnancy is smooth and the fetal development is normal.

Although this is the case, the medication should still be used with caution. The physiology of pregnancy is special, and the principle of medication is not to use it easily if it is not necessary. If a pregnant woman has a disease that requires azelaic acid, she should seek medical attention first. The doctor should comprehensively weigh the specific condition of the pregnant woman and the age of pregnancy. If it is really needed, the lowest effective dose and the shortest course of treatment should be selected, and the condition of the mother and

In summary, the safety of azelaic acid during pregnancy is supported by certain evidence, but the clinical evidence remains to be enriched. For the health of mothers and babies, the choice of medication requires full communication and careful decision between doctors and patients.