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345trimethoxybenzaldehyde applications properties synthesis

Related records of 3,4,5-trimethoxybenzaldehyde
1. Its properties
3,4,5-trimethoxybenzaldehyde, in the shape of white to light yellow crystalline powder. It has a special aromatic odor. Its melting point is between 83 and 85 degrees Celsius, and it is easily soluble in organic solvents such as ethanol and ether, but difficult to dissolve in water. The chemical properties of this substance are stable, but in the environment of strong acid and alkali, it may cause chemical reactions to cause structural changes.

Second, the method of synthesis
Synthesis of 3,4,5-trimethoxybenzaldehyde, which is often used as the starting material of 3,4,5-trimethoxytoluene. First, 3,4,5-trimethoxytoluene is oxidized to 3,4,5-trimethoxybenzoic acid with an appropriate oxidizing agent, such as a combination of manganese dioxide and sulfuric acid. After esterification, 3,4,5-trimethoxybenzoic acid and methanol are catalyzed by concentrated sulfuric acid to form 3,4,5-trimethoxybenzoate methyl ester. Then, 3,4,5-trimethoxybenzoate methyl ester is reduced to 3,4,5-trimethoxybenzool with a reducing agent, such as lithium aluminum hydride. Finally, 3,4,5-trimethoxybenzool is converted into 3,4,5-trimethoxybenzaldehyde by oxidation with manganese dioxide and other oxidizing agents.

III. Wide range of uses
In the field of medicine, 3,4,5-trimethoxybenzaldehyde is an important intermediate. It can be used to synthesize drugs with specific biological activities, such as some anti-tumor drugs. Due to its special structure, it can impart unique pharmacological properties to drug molecules, help drugs to better combine with targets, and improve curative effect. In the fragrance industry, it can be used as a fragrance component due to its aromatic properties. It can add a unique aroma to fragrance formulations and is widely used in the formulation of perfumes, cosmetics and food flavors to increase the charm of product aroma. In the field of organic synthesis, it is a key building block for the construction of complex organic molecules. With its aldehyde and methoxy reactivity, it can synthesize various functional organic compounds through a variety of organic reactions, such as condensation reactions, addition reactions, etc.