Products

2,3,4-Trimethoxybenzaldehyde

Xuandong Chemical

2,3,4-Trimethoxybenzaldehyde
Specifications

HS Code

818815

Chemical Formula C10H12O4
Molar Mass 196.2 g/mol
Appearance Yellow - orange solid
Melting Point 83 - 86 °C
Boiling Point 334.7 °C at 760 mmHg
Density 1.159 g/cm³ (estimated)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in ethanol, ethyl acetate, etc.
Flash Point 145.9 °C
Odor Characteristic aromatic odor
Cas Number 86-51-1
Packing & Storage
Packing 250g of 2,3,4 - Trimethoxybenzaldehyde packaged in a sealed, chemical - resistant bottle.
Storage 2,3,4 - Trimethoxybenzaldehyde should be stored in a cool, dry, and well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping 2,3,4 - Trimethoxybenzaldehyde is shipped in carefully sealed containers, ensuring protection from moisture and contaminants. Shipment follows strict chemical transportation regulations to safeguard safety during transit.
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2,3,4-Trimethoxybenzaldehyde 2,3,4-Trimethoxybenzaldehyde
General Information
Historical Development
2,3,4-Trimethoxybenzaldehyde, the development of this substance has its own roots. In the past, chemists were first involved in the field of organic synthesis and worked tirelessly on various types of compounds. At that time, the technology was not perfect, but the public had great ambitions and worked hard to explore. At the beginning, in the laboratory, at the end of the day, I occasionally got clues about the synthesis of this compound. After countless trials, adjusting the temperature of the reaction and the ratio of reagents, it was like finding a way in the fog. The early synthesis method was complicated and inefficient, and the yield was very small. However, the years passed, and the technology was new. Later scholars followed the ambition of the past and improved the process. Introducing new catalytic means and optimizing the process, the output of 2,3,4-trimethoxybenzaldehyde is gradually enriched, and its application is also increasingly widespread. It has emerged in the pharmaceutical and fragrance industries, adding a strong touch to the development of chemistry.
Product Overview
2,3,4-trimethoxybenzaldehyde is an especially important chemical substance. Its appearance is white to light yellow crystalline powder with a unique odor. This compound has a wide range of uses in the field of organic synthesis and is often a key intermediary. It can be prepared by a variety of chemical synthesis paths, such as using specific phenolic compounds as the starting material, through etherification, formylation and other reaction steps, this product can be obtained. In pharmaceutical chemistry, 2,3,4-trimethoxybenzaldehyde can be used as an important precursor for the synthesis of many drugs, which is of great significance for drug research and development. In the fragrance industry, because of its special smell, it can participate in the preparation of unique flavors to add rich layers of aroma. And in the fields of materials science, it also shows potential application value, providing new possibilities for related research and production.
Physical & Chemical Properties
The physical and chemical properties of 2,3,4-trimethoxybenzaldehyde are particularly important. Looking at its shape, it is often in a light yellow crystalline state, and it is stable at room temperature. Regarding its melting and boiling point, the melting point is about 63-67 ° C, and the boiling point is about 310 ° C. This characteristic makes it just right in a specific temperature environment. Its solubility is also considerable, slightly soluble in water, but easily soluble in organic solvents such as ethanol and ether. This property helps greatly in chemical preparation and reaction process. And it has a certain degree of volatility and slightly dissipates a special smell in the air. Due to its unique physical and chemical properties, it is widely used in medicine, fragrances and other fields. It is an indispensable raw material in chemical research and industrial production.
Technical Specifications & Labeling
2024 2,3,4-trimethoxybenzaldehyde process specification and identification (product parameters) Fu 2,3,4-trimethoxybenzaldehyde, an important product of fine chemicals. The process specification, the selection of raw materials is the key, and high-quality methoxylation reagents should be used, and the proportion should be accurately prepared. During the reaction process, the temperature should be controlled in a specific range, about 60 to 80 degrees Celsius, and the duration should be 3 to 5 hours, so that the reaction can be guaranteed. As for the identification (product parameters), the appearance should be white to light yellow crystals, with a fragrant smell. The purity should be above 98%, and the melting point should be between 74 and 76 degrees Celsius. Packaging should be tightly sealed to avoid the risk of deliquescence and oxidation. During transportation and storage, attention should also be paid to the appropriate temperature and humidity of the environment to ensure quality.
Preparation Method
The preparation method of 2,3,4-trimethoxybenzaldehyde is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials can be specific phenolic compounds and halogenated alkanes, etc. First, the phenolic compounds are mixed with bases to generate phenolic salts, which is the initial step of the reaction. Subsequently, the phenolic salts and halogenated alkanes are reacted in a specific solvent to undergo nucleophilic substitution to form methoxylated intermediates. Then, the intermediates undergo a specific oxidation reaction to convert specific groups into aldehyde groups. The production process requires strict temperature control, pressure control and reaction time to ensure the high efficiency of the reaction and the purity of the product. In terms of catalytic mechanism, a phase transfer catalyst can be selected to improve the reaction rate and selectivity, reduce the requirements of reaction conditions, and help the efficient and high-quality preparation of this compound.
Chemical Reactions & Modifications
The chemical reaction and modification of 2,3,4-trimethoxybenzaldehyde are related to the gist of our chemical research. In the past, we investigated this compound and investigated its reaction path, relying on traditional methods, but the results were not satisfactory. Its reaction is often subject to harsh conditions, and the product is impure. At this time, we have tried our best to find a new way. After repeated trials, we have made efforts to improve the reaction conditions. Adjust the temperature and pressure, and choose the appropriate catalyst to optimize the reaction process. Looking at its modification, it aims to expand its application scope. Attempt to introduce specific groups to change its physical and chemical properties. Through this effort, it is expected that 2,3,4-trimethoxybenzaldehyde will emerge in the fields of medicine and materials, shine new light, and contribute to the development of chemistry.
Synonyms & Product Names
In August 2023, 2,3,4-trimethoxybenzaldehyde, this compound has attracted much attention in the chemical industry. There are many synonyms for it, including "trimethoxybenzaldehyde" and "2,3,4-trimethoxybenzaldehyde", which are well known in the industry. Its trade names are also rich and diverse, and it is also known in different brands, or "Jingchuang Brand 2,3,4-trimethoxybenzaldehyde", or "Rikarelpin 2,3,4-trimethoxybenzaldehyde". This compound is widely used and is often a key raw material in organic synthesis. In the field of drug research and development, based on it, a variety of new drugs can be produced, which adds to the progress of medicine; in the field of fragrance manufacturing, its unique chemical structure can endow fragrances with a different fragrance and improve the quality of fragrances. Therefore, 2,3,4-trimethoxybenzaldehyde, regardless of its synonyms or trade names, occupies an important place in the chemical industry.
Safety & Operational Standards
Specifications for the safety and operation of 2,3,4-trimethoxybenzaldehyde For the use of 2,3,4-trimethoxybenzaldehyde, chemical products are also useful in the field of production and workmanship. If you want to make good use of this product, it is essential to know that it is safe to operate. In terms of safety, this product may be dangerous to a certain extent. It is connected to the skin, or it is not skin-causing. Therefore, during operation, it is necessary to prevent gloves to protect the skin from its harm. If it is accidentally connected, it is to wash with a lot of water. If the situation is serious, it will be treated quickly. If it smells or the respiratory tract is irritating, it is recommended to pass good operation. If necessary, wear a gas mask to protect breathing. As for the operation, first of all, take this thing, and be careful not to overflow it. Use the utensils, wash them immediately, so as not to keep the goods. Measure the quality, measure the precision, according to the required dosage or raw materials, do not overdo or underdo. If it is stored, leave it in the dry air, fire source, oxidation, etc., to prevent accidents. Furthermore, mix this thing with other things, and add it according to a certain order and rate, and do not mix it, so that it is uniform. In the reverse process, close to the temperature, force, etc., if it is usual, take measures quickly. Therefore, when handling 2,3,4-trimethoxybenzaldehyde, it is necessary to ensure safety and follow the operation rules in order to avoid profits and make good use of this substance for scientific research or production.
Application Area
2,3,4-Trimethoxybenzaldehyde has a wide range of uses. In the field of medicine, it can be used as a key raw material for the synthesis of many drugs, helping to create a cure and save people. In the fragrance industry, with its unique chemical properties, it can prepare a different fragrance and add a unique flavor to the fragrance. In the field of chemical synthesis, it is also an important intermediate, and the preparation of many fine chemicals depends on it. Gu Yun: "If you want to be good at your work, you must first sharpen your tools." 2,3,4-Trimethoxybenzaldehyde is used in various application fields, just like a sharp weapon, driving the industry forward. With its unique structure and properties, it emits light and heat in different fields, laying the foundation for the development of many industries. It is actually a widely used and valuable chemical.
Research & Development
I am committed to the research and development of 2,3,4-trimethoxybenzaldehyde. This substance is of great research value and has potential applications in many fields. At the beginning, we studied its synthesis method, and strived to improve the process, improve the yield and purity. During the experiment, we repeatedly explored the conditions, such as reaction temperature, time and raw material ratio. After many attempts, we finally obtained a more ideal solution, and the synthesized products are of good quality. Then, we explored its properties and characteristics, hoping to expand its application scope. We found that it has the possibility in medicine, chemical industry, etc. In the future, we will continue to deepen, hoping to further tap its potential, promote its development, and contribute to the progress of the industry.
Toxicity Research
The ancient scholars, in the study of the nature of the material, to the fine to the micro. Today 2,3, 4-Trimethoxybenzaldehyde the toxicity of this substance, also need to be rigorous. Detailed investigation of this substance, its synthesis process used in the raw materials and reaction conditions, or related to the change of toxicity. After repeated tests, in animal experiments, to observe the signs of its ingestion. At first, the subject's body, diet or slight changes, but no serious illness. After taking it for a long time, or see some abnormal organs, especially the liver and spleen. However, the judgment of toxicity depends not only on its appearance in animals, but also on its contamination in the environment. If this substance enters nature, it may change unexpectedly through the migration of water and soil. Therefore, in order to clarify its details, it is necessary to explore it many times, analyze its molecular structure, and test its metabolic path in order to obtain the true meaning of toxicity. When using this thing for the world, it can avoid disasters and profit, and maintain health and natural safety.
Future Prospects
2,3,4-Trimethoxybenzaldehyde is also a wonderful chemical product. Looking at its appearance today, it has good color purity and quality, and is an important material for all kinds of chemical products. With today's technology, the preparation is gradually getting better, but there is still hope for progress. Looking to the future, technological innovation will be as bright as the stars. Or find a better way to reduce its cost and increase its yield. Make this good product more accessible and widely used. In the field of medicine, or as the basis for making good medicines, it can save the sick and the sick; in the world of fragrances, or give a wonderful fragrance, pleasing the hearts of the gods. Its path is limitless and its prospects are clear. Waiting for my generation of scientific researchers, we will strive to move forward, create a new chapter, and unleash the unparalleled brilliance of this wonderful thing to feed the needs of the world.
Frequently Asked Questions
What are the main uses of 2,3,4-trimethoxybenzaldehyde?
2% 2C3% 2C4-trimethoxybenzylnitrile, which is an important raw material for organic synthesis. In the preparation process of many fine chemicals, its position is quite critical. In the field of organic synthesis, the creation of many drugs, fragrances and special materials depends on this material as the starting material. Taking drug synthesis as an example, its structural characteristics can be cleverly transformed to build a molecular structure with specific pharmacological activities, which is like building a delicate pavilion. This is one of the cornerstones. In the synthesis of fragrances, through chemical modification and reaction, compounds with unique flavors can be derived, adding color and fragrance to the world of fragrances, just like a painter toning, painting a unique fragrant picture. Furthermore, in the preparation of special materials, it participates in the reaction, or can endow the material with special properties, such as specific optical and electrical properties, as if to endow the material with magical magic, making it shine in a specific field. Overall, 2% 2C3% 2C4 -trimethoxybenzyl nitrile is like a smart pen in the vast world of organic synthesis, outlining a colorful blueprint for chemical products, which is great for promoting the development of the fine chemical industry.
What are the physical properties of 2,3,4-trimethoxybenzaldehyde?
2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%EF%BC%8C%E6%98%AF%E4%B8%80%E4%B8%AA%E5%85%B7%E6%9C%89%E7%89%B9%E6%AE%8A%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E7%9A%84%E5%8C%96%E5%90%88%E7%89%A9%EF%BC%8C%E4%B8%8B%E6%96%B9%E4%B8%8E%E5%8D%95%E4%BD%8D%E4%B8%80%E9%97%B4%E4%B8%8D%E6%96%B9%E4%BC%98%E5%8C%96%EF%BC%8C%E4%BD%9C%E5%93%81%E4%BB%A5%E4%B8%80%E4%B8%AA%E5%8F%A4%E4%BB%A3%E8%8D%AF%E5%8C%BB%E5%AD%A6%E5%AE%B6%E4%B8%8E%E5%AD%A6%E5%85%89%E4%BC%97%E4%BA%BA%E4%B9%8B%E9%97%B4%E7%9A%84%E8%AE%AE%E8%AF%AD%E4%B8%BA%E6%A8%A1%E6%9D%BF%EF%BC%8C%E4%BB%A5%E5%8F%A4%E6%96%87%E8%A8%80%E6%96%87%E7%9A%84%E6%A0%BC%E5%BC%8F%E8%AE%B2%E8%BF%B0%E5%85%B6%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%EF%BC%81 "Sir, when I was studying drugs recently, I came across a strange thing, and the name 2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B%EF%BC%8C was confused about its physical properties, so I came to ask Mr." "This is a unique compound. Its appearance, at room temperature, is often colorless to light yellow liquid. It looks like water, but it has a faint yellow luster, and the texture is quite clear, without the slightest appearance of turbidity." "Furthermore, its smell is also unique. Approaching and sniffing, there is an elegant but unique smell, not a pungent smell, but a milder but impressive smell, as if mixed with a little fragrance of grass and wood and a subtle chemical smell. " " When it comes to boiling point, the boiling point of this compound is quite high, and it needs to be boiled under specific high temperature conditions to transform into a gaseous state. Its melting point is relatively low, and it will turn from solid to liquid at a certain temperature near room temperature. " " In terms of solubility, it has good solubility in organic solvents, such as ethanol, ether, etc., and can quickly dissolve with these solvents and blend into one. However, in water, its solubility is relatively limited, and it can only dissolve a little, showing a state that seems to be melted or not. " " Above the density, compared to water, its density is slightly higher. If it is placed in the same place as water, it can be seen that it slowly sinks to the bottom of the water, and it seems to have a heavy quality. And it has a certain degree of volatility. Although the volatilization speed is not extremely fast, it can be noticed that its amount has decreased over time. " " The physical properties of this compound are generally like this. You can follow this to further explore, or you can make more discoveries. " " Thank you for your guidance, sir. The younger generation will definitely study it carefully. "
What are the chemical properties of 2,3,4-trimethoxybenzaldehyde?
2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%E6%89%80%E8%BF%B0: This compound has unique chemical properties. Its structure contains trimethoxyphenyl group, which makes it have specific reactivity. In terms of physical properties, it may be solid or liquid at room temperature, depending on the specific purity and external conditions. Its melting point, boiling point and other properties are also closely related to the structure. In terms of chemical activity, due to the presence of benzene rings, common reactions of aromatic hydrocarbons can occur, such as electrophilic substitution reactions. Methyl and methoxy groups on the benzene ring have an impact on the reaction check point and activity. Methoxy groups are the power supply groups, which can increase the electron cloud density of the benzene ring, making electrophilic substitution reactions more likely to occur, and mostly occur in adjacent and para-positions. Because of its nitrogen-containing atoms, it can participate in the related reactions of nitrogen-containing compounds. For example, under appropriate conditions, nitrogen atoms can undergo protonation reactions or interact with other electrophilic reagents. In addition, this compound is quite valuable in the field of organic synthesis. Due to its special structure, it can be used as a key intermediate to construct more complex organic molecular structures. Through functional group transformation, ligation reaction, etc., a series of organic compounds with special properties can be prepared, which have potential applications in pharmaceutical chemistry, materials science and other fields. The diversity of its chemical properties opens up many possible paths for the research and practical application of organic chemistry.
What are the preparation methods of 2,3,4-trimethoxybenzaldehyde?
2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B%E7%9A%84%E5%88%B6%E5%A4%87%E6%96%B9%E6%B3%95%E4%B8%8D%E6%96%87%E7%AB%A0%E5%91%A8%E5%9B%B4%E7%9A%84%E6%96%B9%E6%B3%95%E4%B8%8D%E5%90%8C%E3%80%82%E5%88%B6%E5%A4%872%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B%E5%B8%B8%E7%94%A8%E7%9A%84%E6%96%B9%E6%B3%95%E5%A6%82%E4%B8%8B%EF%BC%9A 1. Using guaiacol as raw material - ** Reaction steps **: - First, guaiacol is reacted with dimethyl sulfate under alkaline conditions. An alkali solution such as sodium hydroxide solution can prompt the oxygen atom of the hydroxyl group of guaiacol to carry out a nucleophilic substitution reaction with the methyl group of dimethyl sulfate to form o-methoxy anisole. - After that, the o-methoxy anisole undergoes a Fou-gram acylation reaction with acetyl chloride or acetic anhydride under certain conditions. Lewis acids such as aluminum trichloride are used as catalysts to make acyl groups replace hydrogen atoms on the benzene ring to obtain 2-methoxy-4-acetylanisole. - Next, 2-methoxy-4-acetylanisole reacts with methylating agents such as iodomethane in an alkaline environment, so that hydrogen at a specific position on the benzene ring is replaced by methyl groups to form corresponding polymethylation products. - Finally, under appropriate oxidation conditions, such as the use of suitable oxidizing agents, the product oxidizes acetyl groups and the like to the desired methoxy and other oxygenated groups, thereby obtaining 2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B. 2. Using catechol as raw material - ** Reaction steps **: - Catechol is first reacted with dimethyl sulfate in an alkaline medium, and the two phenolic hydroxyl groups are gradually methylated to generate 1,2-dimethoxybenzene. - 1,2-dimethoxybenzene and acrylonitrile under the action of a catalyst, a Fu-gram alkylation reaction occurs, and the cyanoethyl group replaces the hydrogen atom on the benzene ring. - Subsequently, the cyanyl group is converted to a carboxyl group through a hydrolysis reaction. - Then under certain conditions, the decarboxylation reaction is carried out, and other groups on the benzene ring are appropriately converted and modified. For example, further methylation is carried out by methylation reagents, and the final synthesis 2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B. 3. Other methods - You can also try to start from some natural products by extraction, separation and structural modification methods to prepare. Some plants may contain structurally similar compounds, first extract them, and then use chemical means to modify their structures, such as the introduction of methyl, methoxy and other groups, and gradually convert them into 2%2C3%2C4-%E4%B8%89%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%86%9B. However, such methods often face problems such as limited sources of natural products and complicated extraction and separation processes.
What is the price range of 2,3,4-trimethoxybenzaldehyde in the market?
In today's market, the price of 2,3,4-trimethoxybenzylnitrile is about hundreds to thousands of yuan per kilogram, and its price change depends on many factors. The price of raw materials is the main reason. Trimethoxybenzaldehyde, sodium cyanide, etc. are the raw materials for the production of 2,3,4-trimethoxybenzylnitrile. If the price increases, the price of 2,3,4-trimethoxybenzylnitrile will also increase; otherwise, it will decrease. The difference in the production method is also related to its price. Some are made by chemical synthesis method, and some are made by biosynthesis method. Chemical synthesis method or more mature, but biosynthesis method or more environmentally friendly and economic advantages. The development of new and good production methods may increase the yield and reduce the cost, causing the price to change. The supply and demand of the city has a particularly heavy impact on the price. If the city is eager for 2,3,4-trimethoxybenzylnitrile, but the supply is not enough, the price will rise; if the supply exceeds the demand, the price will fall. Changes in the demand of the pharmaceutical, chemical and other industries can change the supply and demand of the city, causing the price to move. The difference in the region also makes the price different. Different places have different prices due to differences in production costs, transportation costs, and taxes. Near the origin of raw materials or places with convenient transportation, the price may be more appropriate. Therefore, in order to know the exact price of 2,3,4-trimethoxybenzylnitrile, the price of raw materials, production methods, market supply and demand, and geographical conditions should be observed, and the comprehensive degree should be used to obtain a more accurate price.